You should be 'checking' it every day at the same time. When you do this, you should i) Top up your coffers so that the max amount of money is used each day (I forget what it is), and ii) Getting your favour back up to 100% so that your money is spent most efficiently.
What I am doing, is 9/10 Points on Maples (I'm trying to God eggs), and then 6/10 on flax.
From what I think, the flax would get me about 80% money back, then the seeds from the birds nest and profit from selling maples will get me at least profit.
Depending on what you do, it can be good profit for little work, like 5 minutes a day, or a sink hole for your cash. s
(Definitely do the sequel quest, so that you can deposit more/spend more per day, and you have more workers to send to work

)